Follow this process to upgrade OpenClinica. In each step, click the link to view detailed instructions for the step:

  1. Back up OpenClinica.
  2. Upgrade OpenClinica.
  3. Configure OpenClinica:
    1. Make any changes needed to the file as described here: Configure the OpenClinica Application.
    2. Ensure that OpenClinica is configured for optimum performance as described here: Configure OpenClinica for Optimum Performance.
    3. You may also need to configure OpenClinica for internationalization should you wish to utilize OpenClinica in different languages. Also, if you need to use some UTF-8 characters in your application, you may need to modify your default connecter configuration. For more information regarding configuring OpenClinica for internationalization and using UTF-8 characters, please refer to
    4. Reboot the system by typing reboot.
  4. Make manual updates to the database.
  5. Start Tomcat by running the following command:
    /etc/init.d/tomcat start